She was born in Los Angeles,
California. Her mother, Lydia, is Cuban. Her father, Victor
Yustman, who is of Italian and French descent, was born in Bogotá, Colombia and raised in Nicaragua. She graduated from Woodcrest
Christian High School in Riverside, California.
After graduating, she had planned on getting a degree in business finance at Loyola Marymount
University before she decided to pursue a career in acting.
Annable made her acting debut at
an early age, playing a young, Spanish-speaking student named Rosa in Kindergarten Cop, and later moved on to
various television shows and movies such as South Beach
and October Road.
In 2007, she starred in the Lifetime
original movie Reckless
Behavior: Caught on Tape and followed it quickly with a lead
role in J. J. Abrams' Cloverfield. She also provided the voice of
the character Amata in Fallout 3. On January
29, 2008, Variety
announced that she would appear in The Unborn,
which was released in 2009.
She is featured in the music
video for "(If You're Wondering If I Want You To) I Want You To"
by Weezer.
She starred as Melanie in the Fox comedy,
Breaking In.
On August 24, 2011, the show was renewed by Fox for thirteen episodes,
scheduled to air in the midseason comedy block.
In October 2011, Annable began
starring in Fox's House as Dr.
Jessica Adams, one of Dr. Gregory House's
newest recruits and made her first appearance in the eighth season premiere
"Twenty Vicodin".
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